Tertiapin LQ

Produktübersicht

• Artikelname: Tertiapin LQ
• Artikelnummer: ISC-KC-030
• Hersteller Artikelnummer: KC-030
• Alternativnummer: ISC-KC-030
• Hersteller: Isca Biochemicals
• Kategorie: Biochemikalien
• Alternative Synonym: TPNLQ, TLQ

Produktbeschreibung

Tertiapin LQ is a selective blocker of Kir1.1 channels, obtained by modifying tertiapin, the toxin from the honey bee venom. Tertiapin LQ blocks Kir1 with high affinity (1.1 nM) and high selectivity (>250-fold) over many commonly studied Kir subtypes. Application of tertiapin LQ locally in the superficial layers of the cerebellar cortex in decerebrate ferrets suppresses normal performance of Purkinje cell pause responses to the conditional stimulus with no detectable effect on spontaneous firing.

Produkteigenschaften

• Molekulargewicht: 2428.03
• NCBI: 2008
• Reinheit: >95% by hplc
• Formulierung: Freeze dried solid
• Sequenz: H-Ala-Leu-Cys*-Asn-Cys*-Asn-Arg-Ile-Ile-Ile-Pro-Leu-Gln-Cys*-Trp-Lys-Lys-Cys*-Gly-Lys-Lys-NH2, disulfide bridges between cysteines 3 - 14 and 5 - 18
• Formel: C106H179N33O24S4
• Target-Kategorie: Potassium channels

Anwendungsbeschreibung

• Anwendungsbeschreibung: ProductType: Peptides