Orexin A (human, rat, mouse), CAS [[205640-90-0]]

Produktübersicht

• Artikelname: Orexin A (human, rat, mouse), CAS [[205640-90-0]]
• Artikelnummer: ISC-OX-050
• Hersteller Artikelnummer: OX-050
• Alternativnummer: ISC-OX-050
• Hersteller: Isca Biochemicals
• Kategorie: Biochemikalien
• Alternative Synonym: Hypocretin 1

Produktbeschreibung

Orexin A (human, rat, mouse) is an endogenous agonist at orexin receptors with Ki values of 20 and 38 nM for OX1 and OX2 receptors respectively. Orexin A stimulates feeding following central administration and is involved in other hypothalamic functions, influencing wakefulness by affecting dopamine, norepinephrine, histamine and acetylcholine systems to stabilize sleep cycles. An absence of orexin A causes narcolepsy, and in animal models, it can alleviate cognitive deficits caused by loss of sleep.

Produkteigenschaften

• Molekulargewicht: 3561.12
• NCBI: 1998
• Reinheit: >95% by hplc
• Formulierung: Freeze dried solid
• Sequenz: Glp-Pro-Leu-Pro-Asp-*Cys-*Cys-Arg-Gln-Lys-Thr-*Cys-Ser-*Cys-Arg-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2 (*disulphide bridges between cysteines 6 and 12, and cysteines 7 and 14)
• CAS Nummer: [205640-90-0]
• Formel: C152H243N47O44S4
• Target-Kategorie: Orexin receptors

Anwendungsbeschreibung

• Anwendungsbeschreibung: ProductType: Peptides