Cynomolgus Latent GDF-8 Protein (pro&latent) (GDF-CM108)

Produktübersicht

• Artikelname: Cynomolgus Latent GDF-8 Protein (pro&latent) (GDF-CM108)
• Artikelnummer: KAB-GDF-CM108
• Hersteller Artikelnummer: GDF-CM108
• Alternativnummer: KAB-GDF-CM108-100UG, KAB-GDF-CM108-500UG
• Hersteller: KactusBio
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Monkey
• Alternative Synonym: Myostatin, GDF8, Latent GDF8, Mstn

Produktbeschreibung

Recombinant Cynomolgus Latent GDF-8 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Gly19-Ser375.

Produkteigenschaften

• Molekulargewicht: The protein has a predicted MW of 41.64 kDa. Due to glycosylation, the protein migrates to 13-15 kDa, 38-41 kDa and 48-52 kDa based on Bis-Tris PAGE result.
• Tag: N-His
• UniProt: Q95J86
• Puffer: Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Expression System: HEK293
• Reinheit: > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
• Formulierung: Lyophilized
• Sequenz: Gly19-Ser375
• Target-Kategorie: GDF-8

Bilder

The purity of Cynomolgus Latent GDF-8 is greater than 95% as determined by SEC-HPLC.

Cynomolgus Latent GDF-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Immobilized Cynomolgus Latent GDF-8, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Apitegromab, hFc Tag with the EC50 of 15.3ng/ml determined by ELISA.

Immobilized Cynomolgus Latent GDF-8, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 28.2ng/ml determined by ELISA.

Loaded Apitegromab, hFc Tag on ProA-Biosensor can bind Cynomolgus Latent GDF-8, His Tag with an affinity constant of 23.00 nM as determined in BLI assay (Gator Prime).