Cynomolgus Latent GDF-8 Protein (pro&latent) (GDF-CM108)
Biozol Catalog Number:
KAB-GDF-CM108
Supplier Catalog Number:
GDF-CM108
Alternative Catalog Number:
KAB-GDF-CM108-100UG, KAB-GDF-CM108-500UG
Manufacturer:
KactusBio
Category:
Proteine/Peptide
Species Reactivity:
Monkey
Alternative Names:
Myostatin, GDF8, Latent GDF8, Mstn
Recombinant Cynomolgus Latent GDF-8 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Gly19-Ser375.
Molecular Weight:
The protein has a predicted MW of 41.64 kDa. Due to glycosylation, the protein migrates to 13-15 kDa, 38-41 kDa and 48-52 kDa based on Bis-Tris PAGE result.
Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Expression System:
HEK293
Purity:
> 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
Form:
Lyophilized
Sequence:
Gly19-Ser375
Target:
GDF-8
The purity of Cynomolgus Latent GDF-8 is greater than 95% as determined by SEC-HPLC.
Cynomolgus Latent GDF-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Immobilized Cynomolgus Latent GDF-8, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Apitegromab, hFc Tag with the EC50 of 15.3ng/ml determined by ELISA.
Immobilized Cynomolgus Latent GDF-8, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 28.2ng/ml determined by ELISA.
Loaded Apitegromab, hFc Tag on ProA-Biosensor can bind Cynomolgus Latent GDF-8, His Tag with an affinity constant of 23.00 nM as determined in BLI assay (Gator Prime).
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