Human TIGIT Protein (TIG-HM210)

Artikelnummer: KAB-TIG-HM210
Artikelname: Human TIGIT Protein (TIG-HM210)
Artikelnummer: KAB-TIG-HM210
Hersteller Artikelnummer: TIG-HM210
Alternativnummer: KAB-TIG-HM210-100UG, KAB-TIG-HM210-500UG
Hersteller: KactusBio
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Alternative Synonym: TIGIT, VSIG9, VSTM3, WUCAM
Recombinant Human TIGIT Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Met22-Pro141.
Molekulargewicht: The protein has a predicted MW of 39.8 kDa. Due to glycosylation, the protein migrates to 48-50 kDa based on Bis-Tris PAGE result.
Tag: C-hFc (IgG1)
UniProt: Q495A1
Puffer: Lyophilized from 0.22µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Expression System: HEK293
Reinheit: > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
Formulierung: Lyophilized
Sequenz: Met22-Pro141
Target-Kategorie: TIGIT
Human TIGIT, hFc Tag captured on CM5 Chip via Protein A can bind Biotinylated Human Nectin-2, His-Avi Tag with an affinity constant of 1.84 uM as determined in SPR assay (Biacore T200).
Human TIGIT on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human TIGIT is greater than 95% as determined by SEC-HPLC.
Immobilized Human TIGIT, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human CD155, mFc Tag with the EC50 of 10.6ng/ml determined by ELISA (QC Test).
Immobilized Biotinylated Human Nectin-2, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human TIGIT, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA.