EPI-001, a selective inhibitor of Androgen Receptor (AR), targets transactivation unit 5 (Tau-5) of the AR. EPI-001 can inhibit transactivation of the AR amino-terminal domain (NTD), with an IC50 of ~6 µM. EPI-001 is also a selective modulator of PPARgamma. EPI-001 is active against castration-resistant prostate cancer[1][2][3].
Molekulargewicht:
394.89
Reinheit:
99.34
CAS Nummer:
[227947-06-0]
Formel:
C21H27ClO5
Target-Kategorie:
Androgen Receptor,Apoptosis,PPAR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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