D-alpha-Hydroxyglutaric acid (disodium) (Standard), CAS [[103404-90-6]] Preis auf Anfrage

Artikelnummer: MCE-HY-100542R
Artikelname: D-alpha-Hydroxyglutaric acid (disodium) (Standard), CAS [[103404-90-6]] Preis auf Anfrage
Artikelnummer: MCE-HY-100542R
Hersteller Artikelnummer: HY-100542R
Alternativnummer: MCE-HY-100542R-100MG,MCE-HY-100542R-50MG,MCE-HY-100542R-25MG,MCE-HY-100542R-5MG,MCE-HY-100542R-10MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: Disodium (R)-2-hydroxyglutarate (Standard)
D-alpha-Hydroxyglutaric acid (disodium) (Standard) is the analytical standard of D-alpha-Hydroxyglutaric acid (disodium). This product is intended for research and analytical applications. D-alpha-Hydroxyglutaric acid disodium (Disodium (R)-2-hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-alpha-Hydroxyglutaric acid disodium is a weak competitive antagonist of alpha-ketoglutarate (alpha-KG) and inhibits multiple alpha-KG-dependent dioxygenases with a Ki of 10.87 mM. D-alpha-Hydroxyglutaric acid disodium increases reactive oxygen species (ROS) production. D-alpha-Hydroxyglutaric acid disodium binds and inhibits ATP synthase and inhibits mTOR signaling[1][2][3][4][5].
Molekulargewicht: 192.08
CAS Nummer: [103404-90-6]
Formel: C5H6Na2O5
Target-Kategorie: ATP Synthase,Endogenous Metabolite,mTOR,Reactive Oxygen Species (ROS),Reference Standards
Anwendungsbeschreibung: MCE Product type: Reference Standards