(S)-Crizotinib (Standard), CAS [[1374356-45-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: (S)-Crizotinib (Standard), CAS [[1374356-45-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-100549R
• Hersteller Artikelnummer: HY-100549R
• Alternativnummer: MCE-HY-100549R-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

(S)-Crizotinib (Standard) is the analytical standard of (S)-Crizotinib (HY-100549). This product is intended for research and analytical applications. (S)-Crizotinib is a potent and selective MTH1 (mutT homologue) inhibitor with an IC50 of 330 nM. (S)-Crizotinib disrupts nucleotide pool homeostasis via MTH1 inhibition, induces an increase in DNA single strand breaks, activates DNA repair in human colon carcinoma cells, and effectively suppresses tumour growth in animal models[1].

Produkteigenschaften

• Molekulargewicht: 450.34
• CAS Nummer: [1374356-45-2]
• Formel: C21H22Cl2FN5O
• Target-Kategorie: Apoptosis,DNA/RNA Synthesis,Reference Standards

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference Standards