(S)-Crizotinib (Standard), CAS [[1374356-45-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-100549R
Supplier Catalog Number:
HY-100549R
Alternative Catalog Number:
MCE-HY-100549R-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
(S)-Crizotinib (Standard) is the analytical standard of (S)-Crizotinib (HY-100549). This product is intended for research and analytical applications. (S)-Crizotinib is a potent and selective MTH1 (mutT homologue) inhibitor with an IC50 of 330 nM. (S)-Crizotinib disrupts nucleotide pool homeostasis via MTH1 inhibition, induces an increase in DNA single strand breaks, activates DNA repair in human colon carcinoma cells, and effectively suppresses tumour growth in animal models[1].
Molecular Weight:
450.34
CAS Number:
[1374356-45-2]
Formula:
C21H22Cl2FN5O
Target:
Apoptosis,DNA/RNA Synthesis,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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