Cl-amidine (hydrochloride), CAS [[1373232-26-8]]

Produktübersicht

• Artikelname: Cl-amidine (hydrochloride), CAS [[1373232-26-8]]
• Artikelnummer: MCE-HY-100574A
• Hersteller Artikelnummer: HY-100574A
• Alternativnummer: MCE-HY-100574A-25MG,MCE-HY-100574A-100MG,MCE-HY-100574A-10MMX1ML,MCE-HY-100574A-10MG,MCE-HY-100574A-5MG,MCE-HY-100574A-50MG,MCE-HY-100574A-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 µM, 6.2 µM and 5.9 µM for PAD1, PAD3, and PAD4, respectively. Cl-amidine hydrochloride induces apoptosis in cancer cells. Cl-amidine hydrochloride induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model[1][2][3][4][5].

Produkteigenschaften

• Molekulargewicht: 347.25
• Reinheit: 99.82
• CAS Nummer: [1373232-26-8]
• Formel: C14H20Cl2N4O2
• Target-Kategorie: Apoptosis,MicroRNA,Protein Arginine Deiminase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound