Cl-amidine (hydrochloride), CAS [[1373232-26-8]]

Product Overview

• Article Name: Cl-amidine (hydrochloride), CAS [[1373232-26-8]]
• Biozol Catalog Number: MCE-HY-100574A
• Supplier Catalog Number: HY-100574A
• Alternative Catalog Number: MCE-HY-100574A-25MG,MCE-HY-100574A-100MG,MCE-HY-100574A-10MMX1ML,MCE-HY-100574A-10MG,MCE-HY-100574A-5MG,MCE-HY-100574A-50MG,MCE-HY-100574A-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 µM, 6.2 µM and 5.9 µM for PAD1, PAD3, and PAD4, respectively. Cl-amidine hydrochloride induces apoptosis in cancer cells. Cl-amidine hydrochloride induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model[1][2][3][4][5].

Product Properties

• Molecular Weight: 347.25
• Purity: 99.82
• CAS Number: [1373232-26-8]
• Formula: C14H20Cl2N4O2
• Target: Apoptosis,MicroRNA,Protein Arginine Deiminase

Application Notes

• Application Notes: MCE Product type: Reference compound