SirReal2 (Standard), CAS [[709002-46-0]] Preis auf Anfrage

Artikelnummer: MCE-HY-100591R
Artikelname: SirReal2 (Standard), CAS [[709002-46-0]] Preis auf Anfrage
Artikelnummer: MCE-HY-100591R
Hersteller Artikelnummer: HY-100591R
Alternativnummer: MCE-HY-100591R-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
SirReal2 (Standard) is the analytical standard of SirReal2 (HY-100591). This product is intended for research and analytical applications. SirReal2 is a potent, isotype-selective Sirt2 inhibitor with an IC50 value of 140 nM and has very little effect on the activities of Sirt3-5. SirReal2 leads to tubulin hyperacetylation in HeLa cells and induces destabilization of the checkpoint protein BubR1. SirReal2 combined with VS-5584 (HY-16585) suppresses tumor growth and extends the survival rate of mice in tumor xenograft model. SirReal2 is is promising for research of cancer, inflammation and neurodegeneration[1][2][3][4].
Molekulargewicht: 420.55
CAS Nummer: [709002-46-0]
Formel: C22H20N4OS2
Target-Kategorie: Reference Standards,Sirtuin
Anwendungsbeschreibung: MCE Product type: Reference Standards