SirReal2 (Standard), CAS [[709002-46-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-100591R
Hersteller Artikelnummer:
HY-100591R
Alternativnummer:
MCE-HY-100591R-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
SirReal2 (Standard) is the analytical standard of SirReal2 (HY-100591). This product is intended for research and analytical applications. SirReal2 is a potent, isotype-selective Sirt2 inhibitor with an IC50 value of 140 nM and has very little effect on the activities of Sirt3-5. SirReal2 leads to tubulin hyperacetylation in HeLa cells and induces destabilization of the checkpoint protein BubR1. SirReal2 combined with VS-5584 (HY-16585) suppresses tumor growth and extends the survival rate of mice in tumor xenograft model. SirReal2 is is promising for research of cancer, inflammation and neurodegeneration[1][2][3][4].
Molekulargewicht:
420.55
CAS Nummer:
[709002-46-0]
Formel:
C22H20N4OS2
Target-Kategorie:
Reference Standards,Sirtuin
Anwendungsbeschreibung:
MCE Product type: Reference Standards
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten