SirReal2 (Standard), CAS [[709002-46-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-100591R
Supplier Catalog Number:
HY-100591R
Alternative Catalog Number:
MCE-HY-100591R-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
SirReal2 (Standard) is the analytical standard of SirReal2 (HY-100591). This product is intended for research and analytical applications. SirReal2 is a potent, isotype-selective Sirt2 inhibitor with an IC50 value of 140 nM and has very little effect on the activities of Sirt3-5. SirReal2 leads to tubulin hyperacetylation in HeLa cells and induces destabilization of the checkpoint protein BubR1. SirReal2 combined with VS-5584 (HY-16585) suppresses tumor growth and extends the survival rate of mice in tumor xenograft model. SirReal2 is is promising for research of cancer, inflammation and neurodegeneration[1][2][3][4].
Molecular Weight:
420.55
CAS Number:
[709002-46-0]
Formula:
C22H20N4OS2
Target:
Reference Standards,Sirtuin
Application Notes:
MCE Product type: Reference Standards
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