AS-605240 (potassium) Preis auf Anfrage
Artikelnummer:
MCE-HY-10109A
| Artikelname: |
AS-605240 (potassium) Preis auf Anfrage |
| Artikelnummer: |
MCE-HY-10109A |
| Hersteller Artikelnummer: |
HY-10109A |
| Alternativnummer: |
MCE-HY-10109A-1UNIT |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| AS-605240 (potassium) is an orally active PI3Kgamma inhibitor (IC50: 8 nM, Ki: 7.8 nM). AS-605240 (potassium) inhibits MCP-1- and CSF1-induced PKB phosphorylation (IC50 values are 0.181 and 0.550 µM, respectively). AS-605240 (potassium) reduces neutrophil recruitment in RANTES (CCL5)- and thioglycolate-induced peritonitis mouse models (EC50 values are 9.1 and 10 mg/kg, respectively). AS-605240 (potassium) ameliorates alphaCII-IA-induced arthritis in mice[1]. |
| Molekulargewicht: |
295.36 |
| Formel: |
C12H6KN3O2S |
| Target-Kategorie: |
Akt,PI3K |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound |
