AS-605240 (potassium) Preis auf Anfrage

Catalog Number: MCE-HY-10109A
Article Name: AS-605240 (potassium) Preis auf Anfrage
Biozol Catalog Number: MCE-HY-10109A
Supplier Catalog Number: HY-10109A
Alternative Catalog Number: MCE-HY-10109A-1UNIT
Manufacturer: MedchemExpress
Category: Biochemikalien
AS-605240 (potassium) is an orally active PI3Kgamma inhibitor (IC50: 8 nM, Ki: 7.8 nM). AS-605240 (potassium) inhibits MCP-1- and CSF1-induced PKB phosphorylation (IC50 values are 0.181 and 0.550 µM, respectively). AS-605240 (potassium) reduces neutrophil recruitment in RANTES (CCL5)- and thioglycolate-induced peritonitis mouse models (EC50 values are 9.1 and 10 mg/kg, respectively). AS-605240 (potassium) ameliorates alphaCII-IA-induced arthritis in mice[1].
Molecular Weight: 295.36
Formula: C12H6KN3O2S
Target: Akt,PI3K
Application Notes: MCE Product type: Reference compound