QX-314 is a membrane-impermeable quaternary Lidocaine (HY-B0185) derivative with sensory-selective blocking effects. QX-314 inhibits acid-induced esophageal hypersensitivity. QX-314 enters jugular ganglion cells via TRPV1 channels, blocks NaV1.8 channels, and thereby inhibits esophageal sensory conduction. QX-314 can alleviate acid-induced esophageal inflammation. QX-314 can be used for the research on gastroesophageal reflux disease (GERD)[1].
Molekulargewicht:
263.40
CAS Nummer:
[21306-56-9]
Formel:
C16H27N2O
Target-Kategorie:
Sodium Channel,TRP Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
