CGP 12177 (()-CGP 12177) is a beta-Adrenergic receptor (beta-AR) ligand. CGP 12177 is a beta3-AR (Ki = 88 nM) agonist with beta1/beta2-AR (Ki = 0.9 nM for beta1, Ki = 4 nM for beta2) antagonist action. CGP 12177 exhibits partial agonist properties for alpha1-AR in rat pulmonary artery. CGP 12177 regulates the expression of ucp and leptin genes in NMRI mice adipose tissues. CGP 12177 can be used for cardiovascular and metabolic disease research[1][2][3][4].
Molekulargewicht:
279.33
CAS Nummer:
[81047-99-6]
Formel:
C14H21N3O3
Target-Kategorie:
Adrenergic Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
