Avapritinib, CAS [[1703793-34-3]]

Produktübersicht

• Artikelname: Avapritinib, CAS [[1703793-34-3]]
• Artikelnummer: MCE-HY-101561
• Hersteller Artikelnummer: HY-101561
• Alternativnummer: MCE-HY-101561-50MG,MCE-HY-101561-100MG,MCE-HY-101561-25MG,MCE-HY-101561-10MMX1ML,MCE-HY-101561-10MG,MCE-HY-101561-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: BLU-285

Produktbeschreibung

Avapritinib (BLU-285) is a highly potent, selective, and orally active KIT and PDGFRA activation loop mutant kinases inhibitor with IC50s of 0.27 and 0.24 nM for KIT D816V and PDGFRA D842V, respectively. Avapritinib (BLU-285) binds the active conformation of the kinase and shows antitumor activity. Avapritinib (BLU-285) attenuates the transport function of both ABCB1 and ABCG2[1][2].

Produkteigenschaften

• Molekulargewicht: 498.56
• Reinheit: 99.85
• CAS Nummer: [1703793-34-3]
• Formel: C26H27FN10
• Target-Kategorie: c-Kit,PDGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound