DC260126 is a potent antagonist of GPR40 (FFAR1). DC260126 dose-dependently inhibits GPR40-mediated Ca2+ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50: 6.28, 5.96, 7.07, 4.58 µM, respectively)[1]. DC260126 could protect MIN6 beta cells from palmitate-induced ER stress and apoptosis[2].
Molekulargewicht:
307.38
Reinheit:
99.74
CAS Nummer:
[346692-04-4]
Formel:
C16H18FNO2S
Target-Kategorie:
Apoptosis,Free Fatty Acid Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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