DC260126 is a potent antagonist of GPR40 (FFAR1). DC260126 dose-dependently inhibits GPR40-mediated Ca2+ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50: 6.28, 5.96, 7.07, 4.58 µM, respectively)[1]. DC260126 could protect MIN6 beta cells from palmitate-induced ER stress and apoptosis[2].
Molecular Weight:
307.38
Purity:
99.74
CAS Number:
[346692-04-4]
Formula:
C16H18FNO2S
Target:
Apoptosis,Free Fatty Acid Receptor
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted