BIIE-0246 (hydrochloride)

Artikelnummer: MCE-HY-101986A
Artikelname: BIIE-0246 (hydrochloride)
Artikelnummer: MCE-HY-101986A
Hersteller Artikelnummer: HY-101986A
Alternativnummer: MCE-HY-101986A-1MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: AR-H 053591 (hydrochloride)
BIIE-0246 hydrochloride (AR-H 053591 hydrochloride) is a potent and selective NPY2R (neuropeptide Y receptor 2) antagonist with an IC50 value of 15 nM for rat [125I]PYY3-36. BIIE-0246 hydrochloride decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 hydrochloride reduces albuminuria in ADR nephropathy[1][2][3].
Reinheit: 99
Formel: C49H57N11O6.xHCl
Target-Kategorie: Neuropeptide Y Receptor
Anwendungsbeschreibung: MCE Product type: Reference compound