BIIE-0246 (hydrochloride)

Catalog Number: MCE-HY-101986A
Article Name: BIIE-0246 (hydrochloride)
Biozol Catalog Number: MCE-HY-101986A
Supplier Catalog Number: HY-101986A
Alternative Catalog Number: MCE-HY-101986A-1MG
Manufacturer: MedchemExpress
Category: Biochemikalien
Alternative Names: AR-H 053591 (hydrochloride)
BIIE-0246 hydrochloride (AR-H 053591 hydrochloride) is a potent and selective NPY2R (neuropeptide Y receptor 2) antagonist with an IC50 value of 15 nM for rat [125I]PYY3-36. BIIE-0246 hydrochloride decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 hydrochloride reduces albuminuria in ADR nephropathy[1][2][3].
Purity: 99
Formula: C49H57N11O6.xHCl
Target: Neuropeptide Y Receptor
Application Notes: MCE Product type: Reference compound