Panobinostat (LBH589, NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities[1][2]. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells[4]. Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma[3].
Molekulargewicht:
349.43
Reinheit:
99.37
CAS Nummer:
[404950-80-7]
Formel:
C21H23N3O2
Target-Kategorie:
Apoptosis,Autophagy,HDAC,HIV
Anwendungsbeschreibung:
MCE Product type: Reference compound
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