Panobinostat (LBH589, NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities[1][2]. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells[4]. Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma[3].
Molecular Weight:
349.43
Purity:
99.37
CAS Number:
[404950-80-7]
Formula:
C21H23N3O2
Target:
Apoptosis,Autophagy,HDAC,HIV
Application Notes:
Reference compound
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