Midostaurin, CAS [[120685-11-2]]

Artikelnummer: MCE-HY-10230
Artikelname: Midostaurin, CAS [[120685-11-2]]
Artikelnummer: MCE-HY-10230
Hersteller Artikelnummer: HY-10230
Alternativnummer: MCE-HY-10230-10MG,MCE-HY-10230-5MG,MCE-HY-10230-50MG,MCE-HY-10230-1MG,MCE-HY-10230-10MMX1ML,MCE-HY-10230-100MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: PKC412, CGP 41251
Midostaurin (PKC412, CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCalpha/beta/gamma, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRbeta and VEGFR1/2 with IC50s ranging from 22-500 nM[1][2]. Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects[3].
Molekulargewicht: 570.64
Reinheit: 99.91
CAS Nummer: [120685-11-2]
Formel: C35H30N4O4
Target-Kategorie: Apoptosis,c-Kit,NO Synthase,PKC,VEGFR
Anwendungsbeschreibung: Reference compound