Midostaurin, CAS [[120685-11-2]]
Catalog Number:
MCE-HY-10230
| Article Name: |
Midostaurin, CAS [[120685-11-2]] |
| Biozol Catalog Number: |
MCE-HY-10230 |
| Supplier Catalog Number: |
HY-10230 |
| Alternative Catalog Number: |
MCE-HY-10230-5MG,MCE-HY-10230-1MG,MCE-HY-10230-10MG,MCE-HY-10230-50MG,MCE-HY-10230-10MMX1ML,MCE-HY-10230-100MG |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| Alternative Names: |
PKC412, CGP 41251 |
| Midostaurin (PKC412, CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCalpha/beta/gamma, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRbeta and VEGFR1/2 with IC50s ranging from 22-500 nM[1][2]. Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects[3]. |
| Molecular Weight: |
570.64 |
| Purity: |
99.91 |
| CAS Number: |
[120685-11-2] |
| Formula: |
C35H30N4O4 |
| Target: |
Apoptosis,c-Kit,NO Synthase,PKC,VEGFR |
| Application Notes: |
MCE Product type: Reference compound |
