Adezmapimod (hydrochloride), CAS [[869185-85-3]]

Produktübersicht

• Artikelname: Adezmapimod (hydrochloride), CAS [[869185-85-3]]
• Artikelnummer: MCE-HY-10256A
• Hersteller Artikelnummer: HY-10256A
• Alternativnummer: MCE-HY-10256A-5MG,MCE-HY-10256A-10MG,MCE-HY-10256A-10MMX1ML,MCE-HY-10256A-50MG,MCE-HY-10256A-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: SB 203580 (hydrochloride), RWJ 64809 (hydrochloride)

Produktbeschreibung

Adezmapimod (SB 203580, RWJ 64809) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38beta2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3beta and PKBalpha with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride does not disrupt JNK activity and is an autophagy and mitophagy activator[1].

Produkteigenschaften

• Molekulargewicht: 413.90
• Reinheit: 99.71
• CAS Nummer: [869185-85-3]
• Formel: C21H17ClFN3OS
• Target-Kategorie: Autophagy,Mitophagy,Organoid,p38 MAPK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound