Adezmapimod (hydrochloride), CAS [[869185-85-3]]

Product Overview

• Article Name: Adezmapimod (hydrochloride), CAS [[869185-85-3]]
• Biozol Catalog Number: MCE-HY-10256A
• Supplier Catalog Number: HY-10256A
• Alternative Catalog Number: MCE-HY-10256A-5MG,MCE-HY-10256A-10MG,MCE-HY-10256A-10MMX1ML,MCE-HY-10256A-50MG,MCE-HY-10256A-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: SB 203580 (hydrochloride), RWJ 64809 (hydrochloride)

Product Description

Adezmapimod (SB 203580, RWJ 64809) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38beta2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3beta and PKBalpha with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride does not disrupt JNK activity and is an autophagy and mitophagy activator[1].

Product Properties

• Molecular Weight: 413.90
• Purity: 99.71
• CAS Number: [869185-85-3]
• Formula: C21H17ClFN3OS
• Target: Autophagy,Mitophagy,Organoid,p38 MAPK

Application Notes

• Application Notes: MCE Product type: Reference compound