Adezmapimod (hydrochloride) (Standard), CAS [[869185-85-3]]

Artikelnummer: MCE-HY-10256AR
Artikelname: Adezmapimod (hydrochloride) (Standard), CAS [[869185-85-3]]
Artikelnummer: MCE-HY-10256AR
Hersteller Artikelnummer: HY-10256AR
Alternativnummer: MCE-HY-10256AR-100MG,MCE-HY-10256AR-50MG,MCE-HY-10256AR-25MG,MCE-HY-10256AR-10MG,MCE-HY-10256AR-5MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: SB 203580 (hydrochloride) (Standard), RWJ 64809 (hydrochloride) (Standard)
Adezmapimod (hydrochloride) (Standard) is the analytical standard of Adezmapimod (hydrochloride). This product is intended for research and analytical applications. Adezmapimod (SB 203580, RWJ 64809) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38beta2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3beta and PKBalpha with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride does not disrupt JNK activity and is an autophagy and mitophagy activator[1].
Molekulargewicht: 413.90
Reinheit: 98.49
CAS Nummer: [869185-85-3]
Formel: C21H17ClFN3OS
Target-Kategorie: Autophagy,Mitophagy,Organoid,p38 MAPK,Reference Standards
Anwendungsbeschreibung: MCE Product type: Reference Standards