Adezmapimod (hydrochloride) (Standard), CAS [[869185-85-3]]

Product Overview

• Article Name: Adezmapimod (hydrochloride) (Standard), CAS [[869185-85-3]]
• Biozol Catalog Number: MCE-HY-10256AR
• Supplier Catalog Number: HY-10256AR
• Alternative Catalog Number: MCE-HY-10256AR-100MG,MCE-HY-10256AR-50MG,MCE-HY-10256AR-25MG,MCE-HY-10256AR-10MG,MCE-HY-10256AR-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: SB 203580 (hydrochloride) (Standard), RWJ 64809 (hydrochloride) (Standard)

Product Description

Adezmapimod (hydrochloride) (Standard) is the analytical standard of Adezmapimod (hydrochloride). This product is intended for research and analytical applications. Adezmapimod (SB 203580, RWJ 64809) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38beta2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3beta and PKBalpha with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride does not disrupt JNK activity and is an autophagy and mitophagy activator[1].

Product Properties

• Molecular Weight: 413.90
• Purity: 98.49
• CAS Number: [869185-85-3]
• Formula: C21H17ClFN3OS
• Target: Autophagy,Mitophagy,Organoid,p38 MAPK,Reference Standards

Application Notes

• Application Notes: MCE Product type: Reference Standards