Carmegliptin, CAS [[813452-18-5]] Preis auf Anfrage

Artikelnummer: MCE-HY-10289
Artikelname: Carmegliptin, CAS [[813452-18-5]] Preis auf Anfrage
Artikelnummer: MCE-HY-10289
Hersteller Artikelnummer: HY-10289
Alternativnummer: MCE-HY-10289-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: RO-4876904
Carmegliptin is an orally active and potent DPP IV inhibitor with a human DPP IV IC50 of 6.8 nM. Carmegliptin binds to the S1 pocket of DPP IV, blocks the degradation of GLP 1, potentiates endogenous GLP 1, increases plasma insulin levels, alleviates hyperglycemia, improves glucose tolerance. Carmegliptin acts as a substrate for human P glycoprotein without inhibiting the transporter, shows low in vitro cell permeability. Carmegliptin can be used for the research of type 2 diabetes, non insulin dependent diabetes mellitus[1][2][3].
Molekulargewicht: 377.45
CAS Nummer: [813452-18-5]
Formel: C20H28FN3O3
Target-Kategorie: Dipeptidyl Peptidase,GLP Receptor,P-glycoprotein
Anwendungsbeschreibung: MCE Product type: Reference compound