Carmegliptin, CAS [[813452-18-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-10289
Supplier Catalog Number:
HY-10289
Alternative Catalog Number:
MCE-HY-10289-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
RO-4876904
Carmegliptin is an orally active and potent DPP IV inhibitor with a human DPP IV IC50 of 6.8 nM. Carmegliptin binds to the S1 pocket of DPP IV, blocks the degradation of GLP 1, potentiates endogenous GLP 1, increases plasma insulin levels, alleviates hyperglycemia, improves glucose tolerance. Carmegliptin acts as a substrate for human P glycoprotein without inhibiting the transporter, shows low in vitro cell permeability. Carmegliptin can be used for the research of type 2 diabetes, non insulin dependent diabetes mellitus[1][2][3].
Molecular Weight:
377.45
CAS Number:
[813452-18-5]
Formula:
C20H28FN3O3
Target:
Dipeptidyl Peptidase,GLP Receptor,P-glycoprotein
Application Notes:
MCE Product type: Reference compound
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