Carmegliptin (hydrochloride), CAS [[813452-14-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: Carmegliptin (hydrochloride), CAS [[813452-14-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-10289A
• Hersteller Artikelnummer: HY-10289A
• Alternativnummer: MCE-HY-10289A-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: RO-4876904 (hydrochloride)

Produktbeschreibung

Carmegliptin (hydrochloride) is an orally active and potent DPP-IV inhibitor with a human DPP-IV IC50 of 6.8 nM. Carmegliptin (hydrochloride) binds to the S1 pocket of DPP-IV, blocks the degradation of GLP-1, potentiates endogenous GLP-1, increases plasma insulin levels, alleviates hyperglycemia, improves glucose tolerance. Carmegliptin (hydrochloride) acts as a substrate for human P-glycoprotein without inhibiting the transporter, shows low in vitro cell permeability. Carmegliptin (hydrochloride) can be used for the research of type 2 diabetes, non-insulin-dependent diabetes mellitus[1][2][3].

Produkteigenschaften

• Molekulargewicht: 450.37
• CAS Nummer: [813452-14-1]
• Formel: C20H30Cl2FN3O3
• Target-Kategorie: Dipeptidyl Peptidase,GLP Receptor,P-glycoprotein

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound