CMPD101 is a potent, highly selective and membrane-permeable small-molecule inhibitor of GRK2/3 with IC50 of 18 nM and 5.4 nM, respectively. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCalpha with IC50s of 3.1 µM , 2.3 µM, 1.4 µM and 8.1 µM, respectively. CMPD101 can be used for the study of heart failure[1].
Molekulargewicht:
466.46
Reinheit:
98.96
CAS Nummer:
[865608-11-3]
Formel:
C24H21F3N6O
Target-Kategorie:
G Protein-coupled Receptor Kinase (GRK),PKC,ROCK
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
