CMPD101 is a potent, highly selective and membrane-permeable small-molecule inhibitor of GRK2/3 with IC50 of 18 nM and 5.4 nM, respectively. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCalpha with IC50s of 3.1 µM , 2.3 µM, 1.4 µM and 8.1 µM, respectively. CMPD101 can be used for the study of heart failure[1].
Molecular Weight:
466.46
Purity:
98.96
CAS Number:
[865608-11-3]
Formula:
C24H21F3N6O
Target:
G Protein-coupled Receptor Kinase (GRK),PKC,ROCK
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
