RWJ52353 (hydrochloride), CAS [[245744-13-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: RWJ52353 (hydrochloride), CAS [[245744-13-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-103216A
• Hersteller Artikelnummer: HY-103216A
• Alternativnummer: MCE-HY-103216A-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

RWJ-52353 hydrochloride is an orally potent, highly selective alpha2D adrenergic receptor agonist (Ki: 1.5 nM) with potential analgesic effects. RWJ-52353 hydrochloride demonstrated analgesic activity in abdominal tests in rats and mice, and improved agitation in mice in the hot plate test and tail flick test. RWJ-52353 hydrochloride also regulates the organic cation transporter (OCT) subtype, inhibiting rOCT1 and rOCT2 with IC50s of 100 µM and 20 µM respectively, it also activates rOCT3, affecting [3H]-1- in cells. Methyl-4-phenylpyridinium ([3H]MPP) transport[1][2].

Produkteigenschaften

• Molekulargewicht: 238.74
• CAS Nummer: [245744-13-2]
• Formel: C11H11ClN2S
• Target-Kategorie: Adrenergic Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound