RWJ52353 (hydrochloride), CAS [[245744-13-2]] Preis auf Anfrage

Product Overview

• Article Name: RWJ52353 (hydrochloride), CAS [[245744-13-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-103216A
• Supplier Catalog Number: HY-103216A
• Alternative Catalog Number: MCE-HY-103216A-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

RWJ-52353 hydrochloride is an orally potent, highly selective alpha2D adrenergic receptor agonist (Ki: 1.5 nM) with potential analgesic effects. RWJ-52353 hydrochloride demonstrated analgesic activity in abdominal tests in rats and mice, and improved agitation in mice in the hot plate test and tail flick test. RWJ-52353 hydrochloride also regulates the organic cation transporter (OCT) subtype, inhibiting rOCT1 and rOCT2 with IC50s of 100 µM and 20 µM respectively, it also activates rOCT3, affecting [3H]-1- in cells. Methyl-4-phenylpyridinium ([3H]MPP) transport[1][2].

Product Properties

• Molecular Weight: 238.74
• CAS Number: [245744-13-2]
• Formula: C11H11ClN2S
• Target: Adrenergic Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound