Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRbeta and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors[1][2].
Molekulargewicht:
396.46
Reinheit:
97.41
CAS Nummer:
[356068-94-5]
Formel:
C22H25FN4O2
Target-Kategorie:
c-Kit,PDGFR,VEGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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