Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRbeta and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors[1][2].
Molecular Weight:
396.46
Purity:
97.41
CAS Number:
[356068-94-5]
Formula:
C22H25FN4O2
Target:
c-Kit,PDGFR,VEGFR
Application Notes:
MCE Product type: Reference compound1
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