PG01, CAS [[853138-65-5]]

Produktübersicht

• Artikelname: PG01, CAS [[853138-65-5]]
• Artikelnummer: MCE-HY-103369
• Hersteller Artikelnummer: HY-103369
• Alternativnummer: MCE-HY-103369-5MG,MCE-HY-103369-1MG,MCE-HY-103369-10MG,MCE-HY-103369-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PG01 is a potent CFTR Cl- channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>E193K, G970R and G551D (CFTR mutants) with Kd values of 0.22 µM, 0.45 µM and 1.94 µM, respectively. PG01 is also effective on deltaF508 (Ka of 0.3 µM). PG01 increases deltaF508-CFTR Cl- current after adding Forskolin[1][2].

Produkteigenschaften

• Molekulargewicht: 439.55
• Reinheit: 98.04
• CAS Nummer: [853138-65-5]
• Formel: C28H29N3O2
• Target-Kategorie: CFTR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound