SKF-83566 (hydrobromide), CAS [[108179-91-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: SKF-83566 (hydrobromide), CAS [[108179-91-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-103430
• Hersteller Artikelnummer: HY-103430
• Alternativnummer: MCE-HY-103430-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

SKF-83566 hydrobromide is a potent, blood-brain permeable and orally active D1-like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor (Ki=11 nM)[1][3]. SKF-83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5.7 µM[2]. SKF-83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta[4]. SKF-83566 can be used for the research of parkinsons disease and nicotine craving alleviation[5].

Produkteigenschaften

• Molekulargewicht: 413.15
• CAS Nummer: [108179-91-5]
• Formel: C17H19Br2NO
• Target-Kategorie: 5-HT Receptor,Adenylate Cyclase,Dopamine Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound