SKF-83566 (hydrobromide), CAS [[108179-91-5]] Preis auf Anfrage

Product Overview

• Article Name: SKF-83566 (hydrobromide), CAS [[108179-91-5]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-103430
• Supplier Catalog Number: HY-103430
• Alternative Catalog Number: MCE-HY-103430-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

SKF-83566 hydrobromide is a potent, blood-brain permeable and orally active D1-like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor (Ki=11 nM)[1][3]. SKF-83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5.7 µM[2]. SKF-83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta[4]. SKF-83566 can be used for the research of parkinsons disease and nicotine craving alleviation[5].

Product Properties

• Molecular Weight: 413.15
• CAS Number: [108179-91-5]
• Formula: C17H19Br2NO
• Target: 5-HT Receptor,Adenylate Cyclase,Dopamine Receptor

Application Notes

• Application Notes: Reference compound