[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P, CAS [[96736-12-8]]

Produktübersicht

• Artikelname: [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P, CAS [[96736-12-8]]
• Artikelnummer: MCE-HY-103544
• Hersteller Artikelnummer: HY-103544
• Alternativnummer: MCE-HY-103544-1MG,MCE-HY-103544-5MG,MCE-HY-103544-10MG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide

Produktbeschreibung

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P, a Substance P derivative, is a biased agonist toward neuropeptide and chemokine receptors. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P activates G12. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P binds to IL-8 and GRP receptors. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P inhibits ERK-2 activation, activates JNK activity. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P stimulates an increase in neutrophil migration and Ca2+ mobilization. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P is also a bombesin antagonist, and inhibits the growth of small cell lung cancer[1][2][3]

Produkteigenschaften

• Molekulargewicht: 1516.83
• Reinheit: 98.48
• CAS Nummer: [96736-12-8]
• Formel: C79H109N19O12
• Target-Kategorie: Bombesin Receptor,Interleukin Related,JNK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Peptides