[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P, CAS [[96736-12-8]]

Product Overview

• Article Name: [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P, CAS [[96736-12-8]]
• Biozol Catalog Number: MCE-HY-103544
• Supplier Catalog Number: HY-103544
• Alternative Catalog Number: MCE-HY-103544-5MG,MCE-HY-103544-1MG,MCE-HY-103544-10MG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide

Product Description

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P, a Substance P derivative, is a biased agonist toward neuropeptide and chemokine receptors. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P activates G12. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P binds to IL-8 and GRP receptors. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P inhibits ERK-2 activation, activates JNK activity. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P stimulates an increase in neutrophil migration and Ca2+ mobilization. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P is also a bombesin antagonist, and inhibits the growth of small cell lung cancer[1][2][3]

Product Properties

• Molecular Weight: 1516.83
• Purity: 98.48
• CAS Number: [96736-12-8]
• Formula: C79H109N19O12
• Target: Bombesin Receptor,Interleukin Related,JNK

Application Notes

• Application Notes: Peptides