Vimirogant (hydrochloride), CAS [[1802678-42-7]]

Artikelnummer: MCE-HY-103637A
Artikelname: Vimirogant (hydrochloride), CAS [[1802678-42-7]]
Artikelnummer: MCE-HY-103637A
Hersteller Artikelnummer: HY-103637A
Alternativnummer: MCE-HY-103637A-5MG,MCE-HY-103637A-10MG,MCE-HY-103637A-1MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: VTP-43742 (hydrochloride)
Vimirogant (VTP-43742) hydrochloride is a potent, selective, and orally active RORgammat inhibitor (Ki=3.5 nM, IC50=17 nM). Vimirogant hydrochloride exhibits >1000-fold selectivity versus the RORalpha and RORbeta isotypes. Vimirogant hydrochloride inhibits Th17 differentiation and IL-17A secretion from mouse splenocytes (IC50=57 nM) without affecting Th1, Th2, or Treg cell differentiation. Vimirogant hydrochloride has the potential for autoimmune disorders research[1][2].
Reinheit: 98.39
CAS Nummer: [1802678-42-7]
Formel: C27H35F3N4O3S.xHCl
Target-Kategorie: ROR
Anwendungsbeschreibung: MCE Product type: Reference compound