NAZ2329 (Standard), CAS [[2809469-05-2]] Preis auf Anfrage
Artikelnummer:
MCE-HY-103693R
Hersteller Artikelnummer:
HY-103693R
Alternativnummer:
MCE-HY-103693R-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
NAZ2329 (Standard) is the analytical standard of NAZ2329 (HY-103693). This product is intended for research and analytical applications. NAZ2329, the first cell-permeable inhibitor of R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs), allosterically and preferentially inhibits PTPRZ (IC50=7.5 µM for hPTPRZ1) and PTPRG (IC50=4.8 µM for hPTPRG) over other PTPs. NAZ2329 binds to the active D1 domain and more potently inhibits PTPRZ-D1 fragment (IC50 of 1.1 µM) than the whole intracellular (D1 + D2) fragment (IC50 of 7.5 µM). NAZ2329 can effectively inhibit tumor growth of the glioblastoma cells and suppress stem cell-like properties[1].
Molekulargewicht:
501.56
CAS Nummer:
[2809469-05-2]
Formel:
C21H18F3NO4S3
Target-Kategorie:
Phosphatase,Reference Standards
Anwendungsbeschreibung:
MCE Product type: Reference Standards
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
