NAZ2329 (Standard), CAS [[2809469-05-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-103693R
Supplier Catalog Number:
HY-103693R
Alternative Catalog Number:
MCE-HY-103693R-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
NAZ2329 (Standard) is the analytical standard of NAZ2329 (HY-103693). This product is intended for research and analytical applications. NAZ2329, the first cell-permeable inhibitor of R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs), allosterically and preferentially inhibits PTPRZ (IC50=7.5 µM for hPTPRZ1) and PTPRG (IC50=4.8 µM for hPTPRG) over other PTPs. NAZ2329 binds to the active D1 domain and more potently inhibits PTPRZ-D1 fragment (IC50 of 1.1 µM) than the whole intracellular (D1 + D2) fragment (IC50 of 7.5 µM). NAZ2329 can effectively inhibit tumor growth of the glioblastoma cells and suppress stem cell-like properties[1].
Molecular Weight:
501.56
CAS Number:
[2809469-05-2]
Formula:
C21H18F3NO4S3
Target:
Phosphatase,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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