Trimetrexate (trihydrochloride), CAS [[1658520-97-8]] Preis auf Anfrage
Artikelnummer:
MCE-HY-10373A
Hersteller Artikelnummer:
HY-10373A
Alternativnummer:
MCE-HY-10373A-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
CI-898 (trihydrochloride)
Trimetrexate (CI-898) trihydrochloride is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate trihydrochloride can also inhibit the growth of various cancer cells. Trimetrexate trihydrochloride can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer[1][2][3][4][5].
