Trimetrexate (trihydrochloride), CAS [[1658520-97-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-10373A
Supplier Catalog Number:
HY-10373A
Alternative Catalog Number:
MCE-HY-10373A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
CI-898 (trihydrochloride)
Trimetrexate (CI-898) trihydrochloride is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate trihydrochloride can also inhibit the growth of various cancer cells. Trimetrexate trihydrochloride can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer[1][2][3][4][5].
