SC75741 is a broad and efficient NF-kappaB inhibitor with an IC50 of 200 nM for p65[1]. SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF-kappaB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins[2].
Molekulargewicht:
565.67
Reinheit:
99.51
CAS Nummer:
[913822-46-5]
Formel:
C29H23N7O2S2
Target-Kategorie:
Influenza Virus,NF-kappaB
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
